Cytosolic inclusions of lysosomal origin
Caused by inhibition of catabolic processes
Lamellar bodies piled with non-degradable cargo
Destined to prevail in a dysfunctional state
Inherited
Induced
Obtained
Defect
Lysosomotropism
Drugs protonated and trapped
Unable to escape
But imprisonment becomes fatality
The CAD induced death
Derives from the displacement
Of interaction between the surface
Of ILVs and phospholipase activities
Intraluminal vesicles, nеgative of charge
Associate with complеxes
To ensure order of
Lysosomal degradation of material derived
From catabolism
Hydrolyzed and utilized
Cytosolic inclusions of lysosomal origin
Caused by inhibition of catabolic processes
Lamellar bodies piled with non-degradable cargo
Destined to prevail in a dysfunctional state
Intraluminal vesicles, negative of charge
Associate with complexes
To ensure order of
Lysosomal degradation of material derived
From catabolism
Hydrolyzed and utilized
Caused by inhibition of catabolic processes
Lamellar bodies piled with non-degradable cargo
Destined to prevail in a dysfunctional state
Inherited
Induced
Obtained
Defect
Lysosomotropism
Drugs protonated and trapped
Unable to escape
But imprisonment becomes fatality
The CAD induced death
Derives from the displacement
Of interaction between the surface
Of ILVs and phospholipase activities
Intraluminal vesicles, nеgative of charge
Associate with complеxes
To ensure order of
Lysosomal degradation of material derived
From catabolism
Hydrolyzed and utilized
Cytosolic inclusions of lysosomal origin
Caused by inhibition of catabolic processes
Lamellar bodies piled with non-degradable cargo
Destined to prevail in a dysfunctional state
Intraluminal vesicles, negative of charge
Associate with complexes
To ensure order of
Lysosomal degradation of material derived
From catabolism
Hydrolyzed and utilized
( Pillars of Cacophony )
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